ANNEX 2. SUMMARY OF IN VITRO AND IN VIVO STUDIES
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Main findings
Reference
Apoptosis in olfactory sensory neurons
Islam et al. (2007)
Upregulated mRNA expression of proapoptotic gene Fas and
pro-inflammatory cytokines in ethmoid turbinates
Simultaneous exposure to lipopolysaccharides magnified
roridin A-induced apoptosis and inflammation in the nasal
tract
High trichothecene-producing strain. Lower proteolytic activity
Both strains.
Increased neutrophils, IL-1β and TNF-α
Reduced collagen IV labelling in spore-induced lung
granulomas
Yike, Rand, Dearborn (2007)
