Issue link: https://hi.iaq.net/i/552698
IAQA 18th Annual Meeting & Indoor Environment and Energy Expo (IE3) The views and opinions herein are those of the volunteer authors and may not reflect the views and opinions of IAQA. The information is offered in good faith and believed to be reliable but it is provided without warranty, expressed or implied, as to the merchantability, fitness for a particular purpose or any other matter. sensitization increased significantly with urinary levels of antimicrobial EDCs, but not with non-antimicrobials, including BPA. While the reported health effects of EDCs arenot completely clear, they are one of the exposure classes typically found with a transition to a Western lifestyle. Given the dramatic increase in allergic diseases in developed countries over the past several decades, many have hypothesized that changes in lifestyle practices and associated exposures may be significant contributors to the allergy epidemic. Conclusions Emerging evidence suggests that co-exposure to allergens and other environmental components can modify the risk of allergic sensitization.Over the past few years, many peer-reviewed studies have widened the scope of investigation related to exposures to allergens and other indoor pollutants. These studies clearly point out that a focus on single exposure classes is unlikely to provide all the answers to the complex questions of how exposures influence our health and risk of disease. The health effects of indoor pollutants, including allergens, tobacco smoke, diesel exhaust, particulate matter, endotoxin, PAHs, and EDCs can vary significantly. Both the indoor environment and the occupants within it represent highly complex systems that require a multi- pronged approach. Additional research is needed to further the understanding of the interactions and mechanisms involved. References (in order of appearance): 1) Salo et al. Exposure to multiple indoor allergens in US homes and its relationship to asthma. Journal of Allergy and Clinical Immunology 2008; 121: 678-84 2) Rosenstreich et al. The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. New England Journal of Medicine 1997; 336: 1356- 63 3) Phipatanakul et al. Mouse allergen I. The prevalence of mouse allergen in inner-city homes. The National Cooperative Inner-City Asthma Study. Journal of Allergy and Clinical Immunology 2000; 106: 1070-74 4) Permaul et al. Allergens in urban schools and homes of children with asthma. Pediatric Allergy and Immunology 2012; 5) Chew et al. Mouse and cockroach allergens in the dust and air in northeastern US inner-city public high schools. Indoor Air 2005; 15: 228-34. 6) Sheehan et al. Mouse allergen in urban elementary schools and homes of children with asthma. Annals of Allergy, Asthma and Immunology 2009; 102:125-30 7) Ahluwalia et al. Mouse allergen is the major allergen of public health relevance in Baltimore City. Journal of Allergy and Clinical Immunology 2013; 132: 830-835 8) Butz et al. A randomized trial of air cleaners and a health coach to improve indoor air quality for inner- city children with asthma and second-hand smoke exposure. Archives of Pediatric and Adolescent Medicine 2011; 165: 741-48 9) McCormack et al. In-home particle concentrations and childhood asthma morbidity. Environmental Health Perspectives 2009; 117: 294-298