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Every breath we take: the lifelong impact of air pollution 21 Mölter A, Simpson A, Berdel D et al. A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project. Eur Respir J 2015; 45:610–24. 22 Gruzieva O, Bellander T, Eneroth K et al. Traffic-related air pollution and development of allergic sensitization in children during the first 8 years of life. J Allergy Clin Immunol 2012;129:240–6. 23 Chen Z, Salam MT, Eckel SP, Breton CV, Gilliland FD. Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study. J Thor Dis 2015;7:46–58. 24 Gehring U, Gruzieva O, Agius RM et al. Air pollution exposure and lung function in children: the ESCAPE project. Environ Health Perspect 2013;121:1357–64. 25 Liu J, Lewis G. Environmental toxicity and poor cognitive outcomes in children and adults. J Environ Health 2014;76:130–8. 26 Fernandez-Twinn DS, Constância M, Ozanne SE. Intergenerational epigenetic inheritance in models of developmental programming of adult disease. Semin Cell Dev Biol 2015;43:85–95. 27 Jiang R, Jones MJ, Sava F, Kobor MS, Carlsten C. Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics. Part Fibre Toxicol 2014;11:71. 28 Janssen BG, Godderis L, Pieters N et al. Placental DNA hypomethylation in association with particulate air pollution in early life. Part Fibre Toxicol 2013;10:22. 29 Hou L, Zhang X, Wang D, Baccarelli A. Environmental chemical exposures and human epigenetics. Int J Epidemiol 2012;41:79–105. 48 © Royal College of Physicians 2016

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